The Syrian Arab Air Force (SAAF) acquired an unknown number of MiG-25s – one of the fastest military aircraft ever fielded – from the late 1970s in four variants: MiG-25P and MiG-25PD interceptors (the former was subsequently upgraded to the PD standard to become the MiG-25PDS), MiG-25RB reconnaissance bombers, and MiG-25PU trainers.

The SAAF was believed to have retired its MiG-25s by 2011. This impression was bolstered by satellite imagery showing numerous MiG-25s left in the open at Tiyas Air Base (also known as T4) rather than stored in hardened aircraft shelters.